Calcipotriol Anhydrous + Clobetasol Ointment

Therapeutic Indication

Psoriasis vulgaris: Indicated for the topical treatment of plaque psoriasis in adults.

Chronic plaque psoriasis: Especially effective in thickened, scaly lesions where keratolysis and anti‑inflammatory action are needed.

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Calcipotriol Anhydrous + Clobetasol

Ointment

This ointment is a combination of a vitamin D₃ analogue and a potent corticosteroid for effective management of psoriasis. Calcipotriol Anhydrous regulates skin cell growth and differentiation, reducing scaling and plaque formation, while Clobetasol provides strong anti-inflammatory and immunosuppressive effects to relieve redness, swelling, and itching. The combination offers faster and more effective symptom control compared to monotherapy and improves overall skin condition.

Speciality	Dermatology \| Anti-psoriatic
Tags	Psoriasis Treatment \| Steroid + Vitamin D Analogue \| Anti-inflammatory
Strength	Clobetasol – 0.05% w/w Calcipotriol Anhydrous – 0.005% w/w
Packing Size	15 gm Tube

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Mechanism

Calcipotriol (Vitamin D analogue): Regulates keratinocyte proliferation and differentiation → reduces scaling and plaque thickness.
Clobetasol Propionate (super‑potent corticosteroid): Anti‑inflammatory, antipruritic, vasoconstrictive → reduces redness and itching.
Combination effect: Synergistic — calcipotriol normalizes cell turnover, clobetasol suppresses inflammation.

Side Effects

Local irritation
itching
burning

Contraindication

Psoriasis vulgaris: Indicated for the topical treatment of plaque psoriasis in adults.
Chronic plaque psoriasis: Especially effective in thickened, scaly lesions where keratolysis and anti‑inflammatory action are needed.

Dosage

As directed by the physician.

DRUG INTERACTIONS

Other topical steroids: Increased risk of side effects
Vitamin D or calcium supplements: Increased risk of hypercalcemia
Keratolytic agents: May enhance absorption and irritation

Warning and Precautions

For external use only
Avoid application on face unless prescribed
Do not exceed recommended weekly dose
Monitor calcium levels in prolonged use
Avoid excessive sun exposure
Wash hands after application
Store in a cool, dry place
Keep out of reach of children

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As a contract manufacturer, DM Pharma Pvt Ltd is not responsible for the marketing or end use of these products and disclaims all liability arising from reliance on this information.
Please consult a healthcare professional before using any medicinal product.